Ethics in Clinical Trials and research

The goal of a clinical research is to develop the generalize knowledge that  improves the human health or increases understanding of a human biology. People who can participate in the clinical research make it possible to secure that knowledge. The path is to finding out whether if a new drug or treatment is safe or effective, for example, to test it on the patient volunteers. But by placing a some people at risk of harm for the good of others, clinical research has a potential to exploit the patient volunteers. The purpose of the ethical guidelines is a both to protect patient volunteers and to the preserve to the integrity of a science.

The ethical guidelines which is place today were primarily response to the past abuses, it was most notorious in which  America was an experiment in the Tuskegee, Alabama, in which the treatment was withheld from the 400 African American men with syphilis so that the scientists could study the course of a disease.A Various ethical guidelines were to developed in the 20th century in response to the such studies.



  • 3.1 Social and clinical value
  • 3.2 Scientific validity
  • 3.3 Fair subject selection
  • 3.4 Favorable risk-benefit ratio
  • 3.5 Independent review

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