Clinical Trials in Cardiology and Neurology

Providing state-of-the-art care for people with brain and nervous system disorders is our most important commitment. As a neurology or neurosurgery patient at Cedars-Sinai,have a access to clinical trials and research aimed at improving testing methods, treatments, quality of life and recovery. These studies are open to people with a broad range of neurological conditions.


Controlled clinical trials are conduct the research that completes the causal argument between a treatment and a disease’s control. Yet, this pinnacle of a clinical research is itself afflicted. Chronic problems with the recruitment failure vitiate the potency of our research efforts. In addition, the collision of end-point multiplicity (the drive to measure multiple end points) with the requirement of statistical parsimony (ie, the need to reduce the number of interpretable end points to control the overall type I error) induces a core inefficiency in clinical trial productivity by reducing the number of endpoints findings that are generalizable to the population at large. Unless a clinical trial lists engage these problems with the vigor and imagination, our pinnacle may be a nothing more than an inflection point leading to decline.


  • 11.1 Effects of ODM-109 in ALS
  • 11.2 Amyotrophic Lateral Sclerosis (ALS)
  • 11.3 Genomic Translation for ALS Care (GTAC)
  • 11.4 The Use of Airway Clearance Devices in ALS
  • 11.5 Brainstorm Clinical Trial for ALS

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