Bioinformatics in Clinical Research

Bioinformatics is a convergence of the biotechnology, genomics and information technology that analyses the data and even itrepresent in the statistical form.  It  even plays an important role in understanding the molecular works that is the basis of life. Bioinformatics is associated with the clinical trials are known as Clinical Bioinformatics. Understanding a relationship between the clinical informatics and a bioinformatics helps in discovering and developing the new diagnostics and therapies for diseases. The clinical application of a bioinformatics is associated with the science and technology and it is to understand molecular mechanism and potential therapies for human diseases.

Clinical bioinformatics is a new and important concept for the development of a diseases-specific biomarkers, and the mechanism-oriented is to understanding and individualized medicine which provides a biological and medical a information to allow for  individualized healthcare. In this review,  we can describe the clinical bioinformatics and its application  and theoretical science. It is also about to understanding the molecular world that adds fuel to the life from evolutionary andmechanistic perspectives[6]Bioinformatics was originally developed for the analysis of biological sequences. But now, it encompasses a wide range of subject areas like structural biology, gene expression and genomics studies (figure1). Bioinformatics is  associated with the clinical trials which has gone through much depth of the studies on different subjects and has provided a number of ways that has never been imagined.


  • 5.1 Role in Drug Development
  • 5.2 Target Identification
  • 5.3 Quantitative structure activity relationship
  • 5.4 Software and bioinformatics tools in clinical trials
  • 5.5 Data management in clinical research

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