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Euro Clinical Trails 2020

About conference

10th International Conference on Clinical Research and Clinical Trials, scheduled during March 20-21, 2020 at Amsterdam, Netherlands. This Clinical Research Conference includes a wide range of Keynote presentations, Oral talks, Poster presentations, Symposia, Workshops, Exhibitions and Career development programs.

ConferenceSeries Organizes 3000+ Global Events Every Year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open access journals  which contains over 100000 eminent personalities, reputed scientists as editorial board and organizing committee members. The conference series website will provide you list and details about the conferences organize worldwide.

Clinical Research Conference is one of the well-established conferences among Pharmaceutical Conferences organized by ConferenceSeries

why to attend?

Clinical Research 2020 Conference is a multidisciplinary program with broad participation with members from around the globe focused on learning about clinical research and its advances. This is your best opportunity to reach the largest assemblage of participants from Clinical Trials, Clinical Research and Epidemiology community that is from academia, clinical research entities, medical groups, related associations, societies and also from government agencies, pharmaceutical, biomedical and medical device industries.

Clinical Research 2020 will discuss various disciplines involved in the pre-clinical research, conduct of clinical trials; it will educate health care researchers about design, operation, organizing, research computing, regulatory aspects and reporting of clinical trials. It promotes better understanding by the general public about the importance of clinical trials in prevention, diagnosis and treatment of disease.

Conduct presentations, distribute information, meet with current and potential scientists, make a splash with new clinical research developments, and receive name recognition at this 2-days event. World renowned speakers and the most recent techniques, developments, the newest updates in Clinical Research and encouraging world toward conducting Clinical Research and Clinical Trials are hallmarks of this conference.

Who should attend and Who You’ll Meet:

Directors/Senior Directors/Executive Directors and Vice Presidents/Senior Vice Presidents/Executive Vice Presidents and Heads/Leaders/Partners of

  • CROs and CMOs
  • Clinical Research Sites
  • Pharma/Biotech and Medical Device industries
  • Hospitals, Associations
  • Clinical research institutes
  • Societies

Medical Directors, Principal Investigators, Methodologists, and other clinical research professionals along with Academicians: University Faculties like Directors, Senior Professors/Assistant Professors/ Associate Professor, Research Scholars, scientists who are related to clinical and medical research.

 

 

Sessions and Tracks

Tract 1: Clinical Trails and innovation

The clinical trial market is enormous. To understand of its scale, and consider that the ClinicalTrials.gov currently lists more than the 280,000 active clinical research studies, and up from just 2,119 active studies in the year 2000. Even with these massive increase in the number of the clinical trials between 2000 and 2018,and the research indicates the market’s value will be also keep growing to reach the $65.2 billion by 2025.Despite  impressive size of the clinical trial market, and the industry faces the several challenges.

The primary challenge is undertaking a clinical trial  cost. A report from the U.S. Department of Health and Human Services estimates that the total cost across Phases I, II, III, and IV of a clinical trial can range from $44 million to $115.3 million, depending on the drug’s therapeutic area. Moreover, fewer than the  one in 10 drugs that are enter the clinical trials make it to the market.

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Tract 2:Clinical Data Management

The Clinical Data Management is the process of the handling data from the clinical trials. The inherent goal of a any clinical data management is the system is to produce and to maintain quality data.  And this department is to involved in the overall collection and in handling of the clinical trial data. And the Data Management teams that develop tools for collection of data at the clinical trial sites, and quality check the collected data for errors and raise flags in case of any discrepancy is identified. They develop the tools for the verification, validation and the quality control of the data gathered during the clinical trial. Clinical data managers to ensure the integrity and the confidentiality of collected data is to maintained at all the times. The Various security controls are to be incorporated into the system to ensure that the data extracted from the  clinical trials is to secure and not to prone to any open threats. The Careers in the Clinical Data Management are verypromising.in This field offers a wide scope of the career options.  At the Quanticate we believe  providing the high quality clinical data management to support the drug development needs to get the drugs to the market as quickly as possible. so the patients have access to the drugs. We provide bespoke solutions tailored to your requirements and provide real time, faster access to data meaning faster decisions can be made to keep patients as safe as possible.

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Tract 3:Ethics in Clinical Trials and research

The goal of a clinical research is to develop the generalize knowledge that  improves the human health or increases understanding of a human biology. People who can participate in the clinical research make it possible to secure that knowledge. The path is to finding out whether if a new drug or treatment is safe or effective, for example, to test it on the patient volunteers. But by placing a some people at risk of harm for the good of others, clinical research has a potential to exploit the patient volunteers. The purpose of the ethical guidelines is a both to protect patient volunteers and to the preserve to the integrity of a science.

The ethical guidelines which is place today were primarily response to the past abuses, it was most notorious in which  America was an experiment in the Tuskegee, Alabama, in which the treatment was withheld from the 400 African American men with syphilis so that the scientists could study the course of a disease.A Various ethical guidelines were to developed in the 20th century in response to the such studies.

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Tract 4: Patient-Centric Clinical Trials

Identifying and addressing unmet patient needs is, and always will be, the ultimate goal of pharmaceutical R&D. Therefore the  new clinical trial models and  technologies behind them should be a harnessed to achieve those goals. In many cases, technology that allows constant monitoring of, and communication with, patients in real time creates the possibility to assess the results of therapies at a level of granularity and over a range of real-world conditions never before imagined – and to intervene in real time if necessary to improve patients’ lives.

The culture of clinical research is evolving from one directed by researchers to one driven by the needs of patients and those who care for them. Among the possibilities for making trials more responsive to patient needs are:

Clinical trials is often to serve as a first point of interaction between a patient and a sponsor company. Nevertheless, clinical teams can lose a sight of this fact when designing a technical components of a clinical studies. The outcome can be a cumbersome trial protocols adding a unnecessary burden on the patients and already in a challenging situation, and, therefore, unhappy patients, low recruitment and a high dropout rates, as well as a low scores on the company perception surveys.

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Tract 5: Bioinformatics in Clinical Research

Bioinformatics is a convergence of the biotechnology, genomics and information technology that analyses the data and even itrepresent in the statistical form.  It  even plays an important role in understanding the molecular works that is the basis of life. Bioinformatics is associated with the clinical trials are known as Clinical Bioinformatics. Understanding a relationship between the clinical informatics and a bioinformatics helps in discovering and developing the new diagnostics and therapies for diseases. The clinical application of a bioinformatics is associated with the science and technology and it is to understand molecular mechanism and potential therapies for human diseases.

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Tract 6: Innovations in Clinical Trials

Clinical trials ar vital to the invention and development of innovative medicines that alter patients to measure longer, healthier lives. As the biopharmaceutical industry works to identify, test and bring new medicines to patients, clinical trials are instrumental in determining the safety and efficacy of a potential new treatment. 

While clinical trials square measure long and complicated, innovative biopharmaceutical firms square measureinvesting the most recent scientific and technical advances to contour the method and make efficiencies. The use of novel trial designs and real-world evidence, for example, is helping to drive these advances, and recently passed legislation is helping to accelerate the uptake of these tools.

As the pace of science continues to evolve, the drug development method – from discovery to approval – remains long and expensive.Developing a new medicine takes an average of 10 or additional years, and therefore the run element alone takes nearly six to seven years.Improving clinical trial design and efficiency thus presents an important challenge that deserves attention from all stakeholders.

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Tract 7: Future of Clinical Trials

A potentially radical solution is the conundrum of a patient recruitment and it is a deceptively simple idea – healthcare professionals which offering a clinical trial to the patients as one care option among many. The idea delivers the triple aim of improved patient experience of care, better population health and reduced per-capita healthcare costs, say some proponents. But what does ‘care option’ mean when talking about drugs that are still in development?

In clinical trials, the drugs are not proven completely safe and efficacious, so we cannot say that a drug is going to treat a patient, as we are still trying to prove it.

With four-out-of-five clinical trials failing to meet the original recruitment targets, a new approaches are needed

“Patients, and especially patients with chronic conditions or life-threatening diseases, are often  looking for a solution, a treatment that may help to improve their quality of life or extend their life. Delays in the clinical trials can cause significant problems to the patients.”

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Tract 8: Clinical and Medical Case Reports

Clinical and Medical Case Reports is an Open Access and the Scientific Journal that offers is an interesting publishing platform globally and the aims to keep scientists, clinicians, medical practitioners, researchers, and students updated on the ongoing research in the relevant area.Outstanding quality articles are welcome to maintain the highest standard of the journal and to achieve high impact factor.

Clinical and theMedical Case Reports is a peer reviewed Journal which that publishes novel research work conducted as case reports in the medical field in various types of Cases,for covering their respective clinical and diagnosis issues

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Tract 9: Pharmacovigilance and Drug Safety

Drug safety (also known as pharmacovigilance), is the science of detection, assessment, understanding and prevention of side effects which allows us to understand more about the risks and benefits of a medicine. 

Adverse drug reactions experienced with the use of  medicinal product may result in the significant morbidity. and mortality. The ultimate goal of pharmacovigillance is to ensure safe use of medicines, minimizing the risks related to the medicinal product and maximizing the benefits. During development of a medicinal product, it undergoes animal testing and establishing its safety and efficacy in humans before permission to market is granted. However, clinical trials are conducted on a small number of patients, ranging to a few thousand, and excluding special populations, e.g., children, pregnant and lactating women, and geriatric patients. 

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Tract10: Artificial Intelligence in Clinical Trials

Artificial intelligence could improve key parts of the clinical trial process, including selection and recruitment and patient monitoring, according to a study published in Trends in Pharmacological Sciences.

It takes between 10 and 15 years and costs between $1.5 and $2.0 billion to bring a new drug to market, researchers noted, and about half of this time and capital is dedicated to clinical trials.

But despite significant investments, clinical trials still have high failure rates, the team stated.

Clinical trial failures are mainly due to poor recruiting and selecting techniques, as well as an inability to effectively monitor patients. Artificial intelligence tools have emerged as a viable way to improve these processes and increase clinical trial success rates, researchers said.

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Tract 11:Clinical Trials in Cardiology and Neurology

Providing state-of-the-art care for people with brain and nervous system disorders is our most important commitment. As a neurology or neurosurgery patient at Cedars-Sinai,have a access to clinical trials and research aimed at improving testing methods, treatments, quality of life and recovery. These studies are open to people with a broad range of neurological conditions.

Controlled clinical trials are conduct the research that completes the causal argument between a treatment and a disease’s control. Yet, this pinnacle of a clinical research is itself afflicted. Chronic problems with the recruitment failure vitiate the potency of our research efforts. In addition, the collision of end-point multiplicity (the drive to measure multiple end points) with the requirement of statistical parsimony (ie, the need to reduce the number of interpretable end points to control the overall type I error) induces a core inefficiency in clinical trial productivity by reducing the number of endpoints findings that are generalizable to the population at large. Unless a clinical trial lists engage these problems with the vigor and imagination, our pinnacle may be a nothing more than an inflection point leading to decline.

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Tract 12: Clinical Trials in Dermatology and Oncology

Clinical trials are the backbone of a modern day medicine. Randomized, double-blinded, placebo-controlled studies are critical for advancement in medicine and dermatology. Skin conditions such as psoriasis and atopic dermatitis are  the most common health problems in the United States. The Clinical trials  which can provide a treatments  not only the offer objective improvements in clinical disease status and also subjective improvements in the quality life of the patients for those who are afflicted with the disease.. In this article, we discuss the processes and resources of a clinical trials unit and the challenges that can be encountered during the study process. It is critical to engage  the clinical trials most effectively which to treat a patients with a new and innovative therapies which  are rooted in trial-validated,and evidence-based medicine

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Tract 13: Globalization of Clinical Trials and Clinical Research

The globalization of a clinical research is a generally late wonder, in which a large portion of these reviews are occurring on a worldwide scale, with a huge increment of the clinical trials in creating nations. Created showcases in the United States, Western Europe, Germany, Japan still produce the lion's share of a clinical trial action. About 31% of a world's clinical trials are apparently directed outside of the United. As indicated by the report China, Japan, India, and Korea are the most dynamic settings for the clinical trials among creating countries. It is anticipated that the Japan as the world's second-biggest pharmaceutical market by 2015.

As per the Clinical trials.gov the aggregate number of studies enlisted in 2016 is 231,756. The rate of studies enlisted from United States is 37%, Non-U.S is 47%. It is evaluated to achieve more than 280,000 review registries by 2017

 because, for example, it gives to access to new treatments to participants; however, it requires discussion and the monitoring of ethical questions related mainly to ensuring the integrity.

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Tract 14: Risk assessment and management in clinical trials

With the  increased in  clinical R&D and a budgetary constraints in the complexities of a clinical development,a risk management has become an essential and integral piece to a clinical trial management to ensure the good return on the investment. The core of a risk management is a identification and  assessment of a risks in the beginning and  it is also continuous basis for a risk-bearing activities in clinical trial. After issuance of a guidance on a Risk-Based Monitoring by FDA, the sponsors/CROs have demonstrated a keen interest in adopting a systematic approach to a risk assessment in clinical trials.Risk assessment is a systematic process for identifying and evaluating events that could be affect the achievement of the clinical study objectives.These documents include FDA’s “Guidance for Industry: Oversight of a Clinical Investigations—A Risk-Based Approach is to Monitoring” and EMA’s “Reflection paper on risk based quality management in the clinical trials”. The focus of the regulators on this concept initiates a discussion of how to introduce and implement, to apply risk management principles to the clinical trials. The applicable guidances for the good clinical practice (GCP), ICH E6 and ISO14155, it state explicitly that the sponsor is responsible for quality assurance and quality control.Risk management concepts can be extracted from  ISO 14971: Risk Management for Medical Devices and ICH Q9: Quality Risk Management. The first step is to define a procedure for conducting this activity. The basic steps for risk management include:the identify and assess risks, mitigate risks, and review risks. Additional steps that are required throughout the process include a communication of risks and a documentation activities.Subtracts

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Market Analysis

The global clinical trial supply and logistics market was valued at US$11.437 billion in 2017 and is projected to expand at a CAGR of 8.02% over the forecast period to reach US$18.164 billion by 2023. Clinical trial supply and logistics play an important role in the efficient conduction and management of clinical trials. In order to make sure that the required study drug is available on time there must be a strategic planning followed by an effective team effort and coordination. The sponsors need to have the right personnel, procedures, facilities, and technology.

  Clinical Trial Supply and Logistics Market forecast

 Global Clinical Trial Supply and Logistics Market by Geography :

By geography, the clinical trial supply and logistics market is segmented as North America, South America, Europe, Middle East and Africa, and Asia Pacific. Furthermore, country level analysis is provided within the regions. North America is anticipated to grow significantly on account of growing pharmaceutical companies’ research and development budget. Moreover, growing complexity of conducting a clinical trial is likely to support the growth of the market in Europe while the favorable regulatory changes supporting the conduct trial will drive the Asia Pacific clinical trial supply and logistics market during the forecast period.The market research provides a detailed analysis of global clinical trial supply logistics market By Geography, By Component etc.

Sample view of clinical trial supply and logistics market by geography

 

Global Clinical Trial Supply and Logistics Market by Component :

By component, the global clinical trial supply and logistics market has been segmented as manufacturing, packaging and labeling, and distribution. Distribution held a significant market share in 2017 on account of increasing research and development expenditure incurred by several companies so as to develop new and improved drugs.

 

 

To Collaborate Scientific Professionals around the World

Conference Date March 20-21, 2020

For Sponsors & Exhibitors

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Journal of Clinical Trials Journal of Clinical Research & Bioethics Journal of Clinical Case Reports

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