Dr. Bhavna Anand
Amity University, Noida
Title: Effect of Chemotherapy on ECG in different stages of Cancer- A Review
Biography
Biography: Dr. Bhavna Anand
Abstract
Cancer is not only the challenging disease but the treatment is so the same. Chemotherapy is the treatment plan that is included as an essential treatment which increases the chances to live in serious cancer stages and their types but chemotherapy induced cardiac dysfunction is the life-threatening complications leading to electrophysiological dysfunctions presented at Electrocardiogram. Studies have presented that Chemotherapy is the cause around 5% of cardiac-toxicities and near 4% the reason of cardiac death in cancer. This study aims to review the literature behind the effect of chemotherapy on the electrocardiogram and its alterations see at various stages and types of cancer. The methodology focused by studying the research literature with the help of the keywords and extracted the data from Google scholars, PubMed, Medline, and Cochrane and had 12060 articles in last 5 years. The articles were further investigated on the basis of inclusion criteria including ECG, no history of cardiac abnormalities, Chemotherapy and Cancer with there stages. 51 articles were left behind after investigation and resulted on ECG parameters as waves, complex and interval and alteration; consisting of different types of drugs, stages and type of cancer. Various alterations on ECG parameters that were QTc prolongation, abnormal ventricular repolarization, increased heart rate, QRS complex abnormalities and the severity to the disease was seen in the increased in stage of cancer as early the cardiac toxicity was noticed and delayed in early cancer diagnosis.
Keywords: Electrocardiogram, Chemotherapy, Stages of cancer